Download PDF
Free download in PDF Chromosomal Aberrations Multiple Choice Questions and Answers for competitive exams. These short objective type questions with answers are very important for Board exams as well as competitive exams. These short solved questions or quizzes are provided by Gkseries.
(1)
Which of the following is not true about inversion?
[A]
Two DNA strands with an inverted segment will not pair
[B]
Inverted chromosomes are generally viable
[C]
Inversion including centromere is known as paracenric
[D]
Inversion can cause chromosome breakage
Answer: Two DNA strands with an inverted segment will not pair
(2)
Which of the following statement is incorrect
[A]
Chromosome number is constant within different species in an ecosystem
[B]
Chromosome number is constant within different somatic cells of an organism
[C]
Chromosome number is constant within individuals in a species in an ecosystem
[D]
All of these
Answer: Chromosome number is constant within different species in an ecosystem
(3)
The size of chromosome is measured during
[A]
Metaphase
[B]
Anaphase
[C]
Prophase
[D]
All Of These
(4)
Euchromatin
[A]
Is Partially Condensed
[B]
Genetically Active Chromatin With Genes
[C]
Stains Lightly
[D]
All Of These
(5)
Chromatin Has
[A]
DNA
[B]
DNA, RNA And Proteins
[C]
DNA And Proteins
[D]
None Of These
Answer: DNA, RNA And Proteins
(6)
A chromosome with a very short arm and a very long arm is termed as
[A]
Sub-metacentric
[B]
Telocentric
[C]
Metacentric
[D]
Acrocentric
(7)
______________ inversions reduce crossing over in ______________
[A]
Pericentric, Heterozygous
[B]
Pericentric homozygous
[C]
Paracentric, Heterozygous
[D]
Paracentric, homozygous
Answer: Pericentric, Heterozygous
(8)
Long pericentric inversions generally don’t act as cross over suppressors. Why?
[A]
Cross over product in this is viable
[B]
Two events of crossing over take place
[C]
Long stretches of DNA recombination not recognized
[D]
Mechanism is different for short and long inversions
Answer: Two events of crossing over take place
(9)
In drosophila male there is no cross over suppression due to pericentric inversion as___________
[A]
They never recombine
[B]
They have only one set of chromosome
[C]
They don’t undergo meiosis
[D]
They always have double cross over
Answer: They never recombine
(10)
How will you recognize a terminal deletion from breakage and loss at the terminal end?
[A]
Terminal break will be sticky
[B]
Deletion will be recognized by trans factors
[C]
Indistinguishable
[D]
Terminal break will lead to shorter chromosome than that due to chunk deletion
Answer: Terminal break will be sticky
(11)
You hybridize two cells one of which carries a deletion mutation on chromosome 1. What will you expect to observe?
[A]
Buckling of chromatin of 2nd cell
[B]
Buckling of chromatin of 1st cell
[C]
No observable difference
[D]
Twisting and loop formation between the two chromatins
Answer: Buckling of chromatin of 2nd cell
(12)
You generate a fluorescent probe against a gene that has been deleted. You expose the DNA to the probe and observe it under fluorescent microscope. What will you see?
[A]
Nothing is seen under fluorescence microscope
[B]
Most parts of the chromosome emits fluorescence
[C]
Fluorescence will correspond to the gene of interest
[D]
There will be a number of regions that emit fluorescence
Answer: Nothing is seen under fluorescence microscope
(13)
Deletion of a region led to over expression of a gene X. What do you conclude from this observation?
[A]
Regulator of gene X is deleted
[B]
No effect on gene X or its regulators
[C]
Part of gene X is mutated
[D]
Promoter of gene X is deleted
Answer: Regulator of gene X is deleted
(14)
Yellow colour of mouse is generated by _________ mutation.
[A]
Deletion
[B]
Translocation
[C]
Duplication
[D]
Inversion
(15)
Which of the following is not true about the Notch gene in Drosophila?
[A]
Notch is lethal in homozygous form
[B]
Notch is recessive to Facet
[C]
It causes a special indentation of the wing margin
[D]
It is expressed in heterozygous form
Answer: Notch is recessive to Facet
(16)
Who coined the term ‘chromatin’ to describe the thread like material of the nucleus?
[A]
Boveri
[B]
W.Roux
[C]
E. Strasburger
[D]
W. Flemming
(17)
The lowest level of chromosome organization is
[A]
30nm Fibre
[B]
Solenoid
[C]
Nucleosome
[D]
None Of These
(18)
Chromosome is thickest during
[A]
Metaphase
[B]
Interphase
[C]
Prophase
[D]
None Of These
(19)
Consider this sequence A—O—B —C—D—E—F, be a DNA sequence where O is the centromere. Which of the following will be a pericentric inversion?
[A]
A—O—E—D—B—F
[B]
D—B—O—A—E—F
[C]
A—O—B—D—E—F
[D]
B—O—A—D—E—F
(20)
What are the results of pericentric inversion with single crossing over?
[A]
2 dicentric and 2 acentric chromosomes
[B]
3 normal chromosome, one abnormal acentric chromosome
[C]
Two normal, one dicentric and one acentric chromosome
[D]
Four normal chromosomes with centriomere in different positions
Answer: Two normal, one dicentric and one acentric chromosome
Take Mock Tests