The Chargaff rules state that the number of purines and pyrimidines are equal (A+G = T + C)in any double-stranded DNA molecules

Q. The Chargaff rules state that the number of purines and pyrimidines are equal (A+G = T + C)in any double-stranded DNA molecules. Watson and Crick later solved the structure of DNA and nitrogen base pairings. Which of the following base pairing rule is true:

A.            Adenine pairs with Guanine and Thymine pairs with Cytosine

B.            Adenine pairs with Thymine and Guanine pairs with Cytosine

C.            Adenine pairs with Cytosine and Guanine pairs with Thymine

D.            DNA base pairing is nonspecific

Answer: Adenine pairs with Thymine and Guanine pairs with Cytosine