Which of them is used to introduce negative supercoiling in DNA?
Answer: Gyrase/ type 2 topoisomerase
What is the term given to the supercoiling of circular DNA?
Which of this factor is not responsible for thermal denaturation of DNA?
The stability and formation of G-quadruplex depends on __________
Answer: Monovalent cation
Name the nitrogenous base which is found in abundance in G-quadruplex?
The third strand of triple helix is paired in which scheme?
Answer: Hoogsteen base pair scheme
Which one of the following statement is INCORRECT for Z-DNA?
Answer: Anti glycosidic bond conformation
How many base pairs are there in every helical turn of Watson-Crick double helix model?
Which form of DNA is described by Watson-Crick model?
Who described the structure of DNA double helix?
Levene investigated and found that the nucleic acid is composed of poly-nucleotides and each nucleotide is composed of one base, a sugar molecule and a phosphate. This was performed on the genome of________________
In the late 1970s non double helical form of DNA was also suggested but was discarded on the basis of certain factors. Which of the following is not a factor responsible?
With respect to the importance of hydrogen bonding and DNA double helix stability, which of the following statements is false?
Answer: Decreases the entropy
In a DNA double helix the bases are held together by hydrogen bonds. These hydrogen bonds are _________
Answer: Non-covalent bonds
The hydrogen bonds formed during A and T bonding occurs between C6NH2 of A and _____
What should be the complementary strand of 3’….ATGGCTTGA….5’?
In 1952, an unambiguous established work in the laboratory of Alexander Todd led to the discovery of _____________
Answer: 3’-5’ phosphodiester linkage regularly links the nucleotides of DNA
In early 1950s high quality X-ray diffraction photographs of DNA suggesting the DNA being double helix and composed of two nucleotide strands. Who took those photographs?
Answer: Rosalind Franklin and Maurice Wilkins
The first X-ray diffraction patterns of DNA were taken in 1938 by ___________
A nucleoside is composed of