Mutation Quiz | Mutation Objective Type Questions and Answers

(21) Mut S recruits how many component(s) to the mismatched site?
[A] 1
[B] 2
[C] 3
[D] 4
Answer: 2
(22) In E. coli mismatches are detected by which repair protein?
[A] Mut H
[B] Mut L
[C] Mut S
[D] Mut D
Answer: Mut S
(23) Normally DNA molecule has A-T, G-C pairing. However these bases can exist in alternative valency status, owing to rearrangements called
[A] point mutation
[B] frame shift mutation
[C] analogue substitution
[D] tautomerisational mutation
Answer: tautomerisational mutation
(24) The action of ultraviolet radiation on DNA to induce mutation is the
[A] formation of thymine dimers
[B] methylation of base pairs
[C] deletion of base pairs
[D] addition of base pairs
Answer: formation of thymine dimers
(25) In mutational event, when adenine is replaced by guanine, it is case of
[A] transition
[B] transcription
[C] transversion
[D] frame shift mutation
Answer: transition
(26) Muller was first to produce induced mutations in ---- by exposing them to X rays
[A] Paramecium
[B] Arabidopsis
[C] Drosophila
[D] Xenopus
Answer: Drosophila
(27) Damage and errors in DNA cause___________
[A] Mutation
[B] DNA repair
[C] Translation
[D] Transcription
Answer: Mutation
(28) Mark the INCORRECT statement about mutation?
[A] Mutation is predestined
[B] Major source of evaluation
[C] Usually deleterious and recessive
[D] It is a reversible process
Answer: Mutation is predestined
(29) Which of the following is NOT a type of reverse mutation?
[A] Back mutation
[B] Intergenic suppressor mutation
[C] Intragenic suppressor mutation
[D] Missense mutation
Answer: Missense mutation
(30) Which of the following is NOT true for loss of function mutation?
[A] Usually recessive
[B] Most common mutation
[C] Increases the activity of the gene
[D] Null allelic mutation
Answer: Increases the activity of the gene
31 Name the term given to the type of mutation which depends on the conditions of the environment?
[A] Forward mutation
[B] Reverse mutation
[C] Conditional lethal mutation
[D] Gain of function mutation
Answer: Conditional lethal mutation
32 What is the detection technique of auxotrophs?
[A] Spread plating
[B] Replica plating
[C] Streaking
[D] Pouring
Answer: Replica plating
33 Name the type of mutation in which the cause of mutation is not known?
[A] Spontaneous mutation
[B] Suppressor mutation
[C] Nonsense mutation
[D] Tyrosine kinase inhibitor
Answer: Mis-sense mutation
34 Addition or deletion of bases causes which kind of mutation?
[A] Transversion
[B] Frameshift mutation
[C] Transition
[D] Transcription
Answer: Frameshift mutation
35 Which of the following chemical mutagen affects only replicating DNA?
[A] Acridine dye
[B] Alkylating agent
[C] Deaminating agent
[D] Base analog
Answer: Base analog
36 What is the overall rate at which new mutations arise spontaneously at any given site on the chromosome per round of replication?
[A] ≈ 10-8 – 10-12
[B] ≈ 10-7 – 10-9
[C] ≈ 10-6 – 10-11
[D] ≈ 10-5 – 10-10
Answer: ≈ 10-6 – 10-11
37 What is the dinucleotide sequence of microsatellites?
[A] CA
[B] AT
[C] CC
[D] GC
Answer: CA
38 By which process miss-incorporated base can change into a permanent mutation?
[A] Replication
[B] Transcription
[C] Translation
[D] Transposition
Answer: Replication
39 How many steps are required to attain mismatch repair?
[A] 1
[B] 3
[C] 2
[D] 4
Answer: 2

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