Protein Synthesis MCQs | Protein Synthesis Multiple Choice Questions and Answers

(1) Conversion of messages carried by mRNA into amino acid sequences is called___________
[A] Translation
[B] Transcription
[C] Replication
[D] DNA repair
Answer: Translation
(2) The following set of RNA is required in the translation process except one, mark the INCORRECT?
[A] tRNA
[B] mRNA
[C] rRNA
[D] Si RNA
Answer: Si RNA

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(3) Name the sequence of RNA, which is recognized by a small subunit of the ribosome.
[A] Shine Dalgarno sequence
[B] Rho utilization site
[C] Upstream sequence
[D] Downstream sequence
Answer: Shine Dalgarno sequence
(4) Which of the following is considered as a start codon?
[A] AGG
[B] GUG
[C] UAG
[D] AUG
Answer: AUG
(5) Mark the one, which is NOT a stop codon?
[A] GGA
[B] UAG
[C] UAA
[D] UGA
Answer: GGA
(6) Which of the following recognize a specific amino acid and its cognate t-RNA molecule?
[A] t-RNA synthetase
[B] Topoisomerase
[C] Ribososme
[D] r-RNA
Answer: t-RNA synthetase
(7) Which of the following inhibitor block translation in eukaryotes?
[A] Tetracycline
[B] Puromycin
[C] Cyclohexamine
[D] None of these
Answer: Cyclohexamine
(8) Name the drug which inhibits the initiation step of translation.
[A] Streptomycin
[B] Cyclohexamine
[C] Tetracycline
[D] Ricin
Answer: Streptomycin
(9) What is correct for protein synthesis?
[A] DNA coding takes place in antiparallel fashion
[B] codes transfer on tRNA
[C] coding is done by DNA strands
[D] codes transfer on mRNA
Answer: codes transfer on mRNA
(10) Reverse transcriptase is
[A] RNA dependent DNA polymerase
[B] RNA dependent RNA polymerase
[C] DNA dependent DNA polymerase
[D] DNA dependent RNA polymerase
Answer: RNA dependent DNA polymerase
(11) Which of the following inactivates the 60S subunit of eukaryotic ribosomes?
[A] Ricin
[B] Chloramphenicol
[C] Diphtheria toxin
[D] Cycloheximide
Answer: Ricin
(12) Which is the third elongation step in bacteria?
[A] Translocation
[B] Binding of an incoming aminoacyl t-RNA
[C] Peptide bond formation
[D] None of above
Answer: Translocation
(13) The role of mRNA in protein synthesis is
[A] It provides genetic blueprint for the protein
[B] It catalyzes the process
[C] It translates genetic code to a specific amino acid
[D] It modifies mRNA molecules prior to protein synthesis
Answer: It provides genetic blueprint for the protein
(14) The role of small nuclear RNAs in protein synthesis is
[A] It modifies mRNA molecules prior to protein synthesis
[B] It translates genetic code to a specific amino acid
[C] It provides genetic blueprint for the protein
[D] It catalyzes the process
Answer: It modifies mRNA molecules prior to protein synthesis
(15) The eukaryotic mRNA binding to the ribosomes is facilitated by
[A] 7-methyl guanosine cap
[B] Shine Dalgarno sequence
[C] T-RNA
[D] Poly-A tail
Answer: 7-methyl guanosine cap
(16) Which of the following blocks the peptidyl transferase of 80S eukaryotic ribosomes?
[A] Cycloheximide
[B] Ricin
[C] Diphtheria toxin
[D] Chloramphenicol
Answer: Cycloheximide
(17) Protein synthesis refers to the
[A] process of formation of amino acids from mRNA
[B] process of formation of amino acids directly from a DNA template
[C] process of formation of mRNA from DNA template
[D] Process of duplicating DNA required for protein synthesis
Answer: process of formation of amino acids from mRNA
(18) Which of the following is not a requirement for protein synthesis?
[A] Spliceosome
[B] Ribosomes
[C] peptidyl transfrase
[D] amino acyl-tRNA synthetase
Answer: Spliceosome
(19) Which is the source of energy for amino acid activation?
[A] ATP
[B] TTP
[C] GTP
[D] All the above
Answer: ATP
(20) Which of the following statement is correct?
[A] Activated amino acid binds to the 5’ end of respective tRNA molecule
[B] there is only one amino acyl-tRNA synthetase in a cell
[C] CTP is required for amino acid activation
[D] Termination codon has no tRNA
Answer: Termination codon has no tRNA

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