In eukaryotes, which of the following DNA polymerase is highly processive and required for the elongation phase of DNA replication?
Q. In prokaryotes, the RNA primer from the lagging strand is removed and replaced by the DNA sequence. This process is catalyzed by an enzyme …………… which possess 5′-3′ exonuclease activity and 5′-3′ polymerase activity.
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In eukaryotes, DNA polymerase alpha is a multi-subunit enzyme with different functions. They include:
Which of the following statement is true regarding an enzyme DNA polymerase that catalyzes the elongation of complementary DNA strand?
The DNA polymerase is a template-directed enzyme that synthesizes new complementary strand from a parent strand but it requires the existing short nucleotide sequence for its elongation. Which of the following enzyme is required for the synthesis of this primer?
DNA replication is bidirectional and anti-parallel. Which of the statement is FALSE regarding the DNA replication?
Q. As the two strands of the double helix are separated, the positive supercoiling interferes with the further unwinding of DNA. Which of the following enzyme makes a break in a strand of DNA to release the supercoiling and facilitate the replication to occur?
Which of the following enzyme has a unique ability to introduce positive and negative supercoiling of the DNA and it is the target for antibacterial agents such as ciprofloxacin/quinolones?
