A 67- year-old army officer in good health previously presented with sudden pain in the great toe

Q. A 67- year-old army officer in good health previously presented with sudden pain in the great toe. Serum uric acid level was high, and a diagnosis of gouty arthritis was made He was advised bed rest, pain killers and Allopurinol. What is the mechanism of action of Allopurinol in lowering serum uric acid levels?

A.            Suicidal inhibition

B.            Noncompetitive inhibition

C.            Allosteric inhibition

D.            Feedback inhibition

Answer: Suicidal inhibition