In lysozyme catalysis, which of the following does not contribute?

Q. In lysozyme catalysis, which of the following does not contribute?

A.            The abnormally high pKa of Glu35

B.            The strained conformation of the D sugar

C.            Formation of a covalent intermediate at Asp52

D.            Formation of a covalent intermediate at Ser195

Answer: Formation of a covalent intermediate at Ser195

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