Which of the following enzyme has a unique ability to introduce positive and negative supercoiling of the DNA and it is the target for antibacterial agents such as ciprofloxacin/quinolones?

Q. Which of the following enzyme has a unique ability to introduce positive and negative supercoiling of the DNA and it is the target for antibacterial agents such as ciprofloxacin/quinolones?

A. DnaA protein

B. DNA helicase

C. DNA gyrase

D. DNA polymerase

Answer: DNA gyrase

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