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Human Reproduction – CBSE Notes for Class 12 Biology

Humans are sexually reproducing and viviparous. The reproductive events in humans include formation of gametes (gametogenesis), i.e., sperms in males and ovum in females, transfer of sperms into the female genital tract (insemination) and fusion of male and female gametes (fertilisation) leading to formation of zygote.

Male reproductive system

The male reproductive system is located in the pelvis region. It includes a pair of testes along with accessory ducts, glands and the external genitalia.

Testes

Testes are located outside the abdominal cavity within a pouch called scrotum.
Scrotum maintains the low temperature of the testes (2-2.5°C lower than the normal body temperature) required for spermatogenesis.

Each testis is oval-shape (length 4-5 cm and width 2-3 cm) and covered by a dense covering called tunica albuginea.

Internally it is divided into about 250 compartments known as testicular lobules.

Each lobule contains 1-3 highly coiled (structural and functional units of testis) called seminiferous tubules in which sperms are produced.

Seminiferous tubule is lined on its inside by two types of cells called male germ cells (spermatogonia) and Sertoli cells.

Male germ cells undergo meiotic divisions finally leading to sperm formation.

Sertoli cells provide nutrition to the germ cells.

Interstitial spaces are present in outside regions of seminiferous tubules which contain small blood vessels and interstitial cells or Leydig cells.

Leydig cells synthesise and secrete the testicular hormones called androgens.

Ducts

The Male sex accessory ducts include rete testis, vasa efferentia, epididymis and vas deferens.

The intratesticular duct system starts with tubuli recti, which are short, straight end segments of the seminiferous tubules. These tubules connect the seminiferous tubules to the highly anastomosing, cuboidal epithelium-lined channels called rete testis.

From rete testis, 10-25 fine tubules arise called vasa efferentia that leave the testis and open into the epididymis.

Epididymis leads to vas deferens that ascends to the abdomen and loops over the urinary bladder.
Diagrammatic sectional view of male pelvis showing reproductive system.

Urinary bladder receives a duct from the seminal vesicle to form ejaculatory duct that runs through the prostate and opens into urethra.

Urethra receives the ducts of prostate gland and the bulbourethral gland (Cowper’s glands) a little ahead and runs through the penis to its external opening called urethral meatus.

Glands

The Male sex accessory glands includes-

A pair of seminal vesicles, a prostate gland and a pair of bulbourethral glands (Cowper’s glands).

The secretion of all these glands is called seminal plasma.

Seminal plasma contains fructose, calcium and some enzymes. It is to provide nutrition to the spermatozoa, while travelling through female reproductive tract.

Seminal plasma along with sperms is called semen.

Secretion of bulbourethral glands also helps in the lubrication of the penis.

External genitalia

External genitalia is the penis. It is made up of special erectile tissue that helps in erection of the penis. The enlarged tip of the penis is called glans penis. It is covered by a loose fold of skin called foreskin or prepuce.

Female reproductive system

The female reproductive system consists of a pair of ovaries along with a pair of oviducts, uterus, cervix, vagina and the external genitalia located in pelvic region. These parts of the system along with a pair of the mammary glands are integrated structurally and functionally to support the processes of ovulation, fertilisation, pregnancy, birth and child care.

Ovaries

Ovaries are the primary female sex organs that produce the female gamete (ovum) and several steroid hormones (ovarian hormones).

These are located one on each side of the lower abdomen.

It is almond-shaped, 2-4 cm in length, 1.5 cm in width.

It is connected to the pelvic wall and uterus by ligaments.

Each ovary is covered by a thin epithelium which encloses the ovarian stroma.

Stroma is divided into two regions, i.e. peripheral cortex and inner medulla.

Oviducts

The female accessory ducts constitute oviducts (Fallopian tubes), uterus and vagina.

Each Fallopian tube is about 10-12 cm long and extends from the periphery of each ovary to the uterus.

The part of oviduct closer to the ovary is funnel-shaped infundibulum.

The edges of infundibulum possess finger-like projections called fimbriae, which help in collection of the ovum after ovulation.

Infundibulum leads to a wider part of the oviduct called ampulla.

Isthmus is the last part of the oviduct, which has a narrow lumen and it joins the uterus.

Uterus

The uterus is single and it is also called womb. The shape of the uterusis like an inverted pear.

Wall of the uterus has three layers of tissue.

Perimetrium is the outermost thin membranous layer, myometrium is the middle thick layer of smooth muscles and endometrium is the innermost glandular layer which lines the uterine cavity.

Uterus opens into the vagina through a narrow cervix, its cavity is called cervical canal, which along with vagina forms birth canal.

Endometrium layer undergoes cyclic changes during menstrual cycle.

Smooth muscles in myometrium contract during parturition to deliver the baby.

Vagina is a muscular tube-like structure that opens to the outside. It receives spermatozoa during insemination and serve as birth canal.

External genitalia

The female external genitalia include mons pubis, labia majora, labia minora, hymen and clitoris.

Mons pubis is a cushion of fatty tissue covered by skin and pubic hair.

Labia majora are fleshy folds of tissue which extend down from the mons pubis and surround the vaginal opening.

Labia minora are paired folds of tissue under the labia majora.

Hymen is a membrane that covers the opening of vagina partially. It gets ruptured during vigorous physical activities or during the first coitus.

Clitoris is a tiny finger-like structure, which lies at the upper junction of the two labia minora above the urethral opening.

Mammary glands

Mammary glands (breasts) are paired structures that contain glandular tissue and variable amount of fat.

Glandular tissue of each mammary gland is divided into 15-20 mammary lobes containing the cluster of cells called alveoli.

The cells of alveoli secrete milk, which is stored in the cavities (lumen) of alveoli.

Alveoli open into mammary tubules. The tubules of each lobe join to form a mammary duct.

Several mammary ducts join to form a wider mammary ampulla, which is connected to lactiferous duct through which milk is sucked out.

Process of Reproduction

The process of reproduction in all humans are carried out phase-wise as discussed below:

  1. Pre-fertilization – Gametes are formed and transferred
  2. Fertilization- formation of zygote after a sperm fertilizes the egg
  3. Post-fertilization- Mitotic division of zygote leading to the formation of an embryo. This reproductive stage is referred to as embryogenesis.

Duration and Stages of Pregnancy

Human gestation lasts for an average of 266 days or 38 weeks or 9 months and these intervals are called as trimesters.

  • 1st trimester (1st 3 months or week 1 – 12) – pre embryonic and embryonic development.
  • 2nd trimester (next 3 months: week 13 – 24) – The fetal development begins.
  • 3rd trimester (next 3 months: week 25 – birth) – At this stage baby continues to grow and mature.
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