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Free download in PDF Antigen and Antibody Multiple Choice Questions & Answers for competitive exams. These short objective type questions with answers are very important for competitive exams like NEET, AIIMS etc. as well as Board exams. These short solved questions or quizzes are provided by Gkseries.
(1)
VDRL test is an example of
[A]
Tube test
[B]
Ring test
[C]
Slide test
[D]
none of these
(2)
Weil-Felix reaction is based on sharing of antigens between
[A]
sheep RBCs and EB virus
[B]
mycoplasma and human O group RBCs
[C]
rickettsial antigens and antigens of certain strains of Proteus
[D]
none of these
Answer: rickettsial antigens and antigens of certain strains of Proteus
(3)
Agglutination reaction is more sensitive than precipitation for the detection of
[A]
Antigens
[B]
Antibodies
[C]
Complement
[D]
Antigen-Antibody Complexes
(4)
In which of the following case a large lattice is formed?
[A]
Antibody is in excess
[B]
Antigens and antibodies are in optimal proportion
[C]
Antigen is in excess
[D]
None of these
Answer: Antigens and antibodies are in optimal proportion
(5)
Ring test is used for
[A]
C-reactive protein test
[B]
Ascoli’s thermoprecipitation test
[C]
typing of streptococci and pneumococci
[D]
all of the above
(6)
Precipitation reaction can be converted into agglutination reaction by coating soluble antigen onto
[A]
bentonite particles
[B]
RBCs
[C]
latex particles
[D]
all of these
(7)
Monoclonal antibody production requires
[A]
mouse splenic lymphocytes
[B]
mouse myeloma cells
[C]
both (a) and (b)
[D]
none of these
(8)
Quellung reaction is used for typing of
[A]
Klebsiella pneumoniae
[B]
Streptococcus pneumoniae
[C]
Both (a) and (b)
[D]
None of these
(9)
Slide agglutination reaction is/are useful for the identification of the culture(s) of
[A]
Shigella
[B]
Vibrio cholerae
[C]
Salmonella
[D]
All of these
(10)
Amount of various immunoglobulin classes can be measured by
[A]
double diffusion in one dimension
[B]
single diffusion in two dimensions
[C]
single diffusion in one dimension
[D]
double diffusion in two dimensions
Answer: single diffusion in two dimensions
(11)
Synthesis of antibodies takes place by which of the following cells?
[A]
Bone marrow cells
[B]
T-cells
[C]
B-cells
[D]
Lymph
(12)
The basic structure of antibodies are______
[A]
Y-shaped
[B]
X-shaped
[C]
Linear
[D]
Hyperbolic
(13)
What is the name of the hypervariable region of immunoglobin, which is responsible for its diversity?
[A]
CDR
[B]
Hinge region
[C]
Epitope
[D]
Agretope
(14)
Name the class of immunoglobulin which has a pentameric structure?
[A]
IgE
[B]
IgG
[C]
IgA
[D]
IgM
(15)
One principal function of the Class I and Class II major histocompatibility complex S proteins is to
[A]
transduce the signal to the T-cell interior following antigen binding
[B]
mediate immunoglobulin class switching
[C]
present antigen for recognition by the T-cell antigen receptor
[D]
stimulate production of interleukins
Answer: present antigen for recognition by the T-cell antigen receptor
(16)
Which immunoglobulin is the principal one found in secretions such as milk?
[A]
IgG
[B]
IgM
[C]
IgA
[D]
IgD
(17)
Who discovered the structure of immunoglobulin by treating it with beta-mercaptoethanol?
[A]
Nisonoff
[B]
Edelman
[C]
Porter
[D]
Whittekar
(18)
Which of the following amino acid is found in the hinge region?
[A]
Alanine
[B]
Aspargine
[C]
Proline and cysteine
[D]
Phenylalanine
Answer: Proline and cysteine
(19)
Which immunoglobulin can pass through placenta?
[A]
IgD
[B]
IgE
[C]
IgM
[D]
IgG
(20)
Which of these immunoglobulins is present in external secretion?
[A]
IgG
[B]
IgM
[C]
IgA
[D]
IgE
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