Q. Which one of the following bioreactor configurations is the basis for a trickling biological filter? (A) Stirred tank (B) Packed bed (C) Air lift (D) Fluidized bed Ans: Packed bed
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Q. Which of the following technique(s) can be used to study conformational changes in myoglobin? P. Mass spectrometry Q. Fluorescence spectroscopy R. Circular dichroism spectroscopy S. Light microscopy (A) P only (B) P and S only (C) Q and R only (D) S only Ans: Q and R only
Q. Which one of the following is NOT a principal component of innate immunity? (A) Mucosal epithelia (B) Dendritic cells (C) Complement system (D) Memory B-cells Ans: Memory B-cells
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Q. Which one of the following metabolic processes in mammalian cells does NOT occur in the mitochondria? (A) Citric acid cycle (B) Oxidative phosphorylation (C) Fatty acid β-oxidation (D) Glycolysis Ans: Glycolysis
Q. Which one of the following is INCORRECT about protein structures? (A) A protein fold is stabilized by favorable non-covalent interactions (B) All parts of a fold can be classified as helices, strands or turns (C) Two non-covalent atoms cannot be closer than the sum of their van der Waals radii (D) The peptide bond
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Q. A mixture contains three similarly sized peptides P, Q and R. The peptide P is positively charged, Q is weakly negative and R is strongly negative. If this mixture is passed through an ion-exchange chromatography column containing an anionic resin, their order of elution will be (A) P, Q, R (B) R, Q, P
Q. Which one of the following BLAST search programs is used to identify homologs of a genomic DNA query in a protein sequence database? (A) blastp (B) blastn (C) blastx (D) tblastn Ans: blastx
Q. Which of the following components constitute a molecular mechanics force field? P. Bond stretching Q. Bond angle bending R. Torsional bond rotation S. Non-bonded interactions (A) P and Q only (B) P, Q and R only (C) P, Q and S only (D) P, Q, R and S Ans: P, Q, R and S
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Q. The repeat sequence of telomere in humans is (A) 5′-TATAAT-3′ (B) 5′-TTAGGG-3′ (C) 5′-GGGCCC-3′ (D) 5′-AAAAAA-3′ Ans: 5′-TTAGGG-3′
Q. If serum is removed from the growth medium of human embryonic kidney cell line (HEK), then the cells will A. Proliferate faster B. Proliferate normally C. Undergo cell cycle arrest D. Undergo immediate apoptosis Answer: Undergo cell cycle arrest
