Mutation Quiz | Mutation Objective Type Questions and Answers

Questions
21 Mut S recruits how many component(s) to the mismatched site?
A 1
B 2
C 3
D 4

Answer: 2
22 In E. coli mismatches are detected by which repair protein?
A Mut H
B Mut L
C Mut S
D Mut D

Answer: Mut S
23 Normally DNA molecule has A-T, G-C pairing. However these bases can exist in alternative valency status, owing to rearrangements called
A point mutation
B frame shift mutation
C analogue substitution
D tautomerisational mutation

Answer: tautomerisational mutation
24 The action of ultraviolet radiation on DNA to induce mutation is the
A formation of thymine dimers
B methylation of base pairs
C deletion of base pairs
D addition of base pairs

Answer: formation of thymine dimers
25 In mutational event, when adenine is replaced by guanine, it is case of
A transition
B transcription
C transversion
D frame shift mutation

Answer: transition
26 Muller was first to produce induced mutations in ---- by exposing them to X rays
A Paramecium
B Arabidopsis
C Drosophila
D Xenopus

Answer: Drosophila
27 Damage and errors in DNA cause___________
A Mutation
B DNA repair
C Translation
D Transcription

Answer: Mutation
28 Mark the INCORRECT statement about mutation?
A Mutation is predestined
B Major source of evaluation
C Usually deleterious and recessive
D It is a reversible process

Answer: Mutation is predestined
29 Which of the following is NOT a type of reverse mutation?
A Back mutation
B Intergenic suppressor mutation
C Intragenic suppressor mutation
D Missense mutation

Answer: Missense mutation
30 Which of the following is NOT true for loss of function mutation?
A Usually recessive
B Most common mutation
C Increases the activity of the gene
D Null allelic mutation

Answer: Increases the activity of the gene
31 Name the term given to the type of mutation which depends on the conditions of the environment?
A Forward mutation
B Reverse mutation
C Conditional lethal mutation
D Gain of function mutation

Answer: Conditional lethal mutation
32 What is the detection technique of auxotrophs?
A Spread plating
B Replica plating
C Streaking
D Pouring

Answer: Replica plating
33 Name the type of mutation in which the cause of mutation is not known?
A Spontaneous mutation
B Suppressor mutation
C Nonsense mutation
D Tyrosine kinase inhibitor

Answer: Mis-sense mutation
34 Addition or deletion of bases causes which kind of mutation?
A Transversion
B Frameshift mutation
C Transition
D Transcription

Answer: Frameshift mutation
35 Which of the following chemical mutagen affects only replicating DNA?
A Acridine dye
B Alkylating agent
C Deaminating agent
D Base analog

Answer: Base analog
36 What is the overall rate at which new mutations arise spontaneously at any given site on the chromosome per round of replication?
A ≈ 10-8 – 10-12
B ≈ 10-7 – 10-9
C ≈ 10-6 – 10-11
D ≈ 10-5 – 10-10

Answer: ≈ 10-6 – 10-11
37 What is the dinucleotide sequence of microsatellites?
A CA
B AT
C CC
D GC

Answer: CA
38 By which process miss-incorporated base can change into a permanent mutation?
A Replication
B Transcription
C Translation
D Transposition

Answer: Replication
39 How many steps are required to attain mismatch repair?
A 1
B 3
C 2
D 4

Answer: 2
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