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Molecular Basis of Inheritance MCQs | Multiple Choice Questions with Answers on Molecular Basis of Inheritance

Questions
1 Fredrick Griffith’s experiment involving Streptococcus pneumonia lead to the discovery of____________
A DNA as genetic material
B RNA as genetic material
C Protein as genetic material
D Transforming principle

Answer:Transforming principle
2 Definite results proving DNA to be genetic material was given by __________
A Fredrick Griffith
B Hershey and Chase
C Avery, Macleod and MacCarty
D Meselson and Stahl

Answer: Avery, Macleod and MacCarty
3 Which of the following statements regarding the mechanism of transformation in Bacillus subtilis is false?
A A competent bacteria contains a DNA receptor/translocation complex
B While translocation of exogenous DNA, both strands gets passage into the cell
C While translocation of exogenous DNA, only one strand gets passage into the cell
D The exogenous DNA recombines and incorporates itself in the chromosome of the recipient cell

Answer:While translocation of exogenous DNA, both strands gets passage into the cell
4 What were the main criteria taken under consideration for the experiment by Hershey and Chase?
A DNA contains phosphorus, protein contains sulfur
B Protein contains phosphorus, DNA contains sulfur
C Both DNA and protein contains phosphorus and not sulphur
D Both DNA and protein contains sulfur and not phosphorus

Answer: DNA contains phosphorus, protein contains sulfur
5 What combination of radiolabelling is correct in case of Hershey and Chase’s demonstration of DNA as genetic material in T2 bacteriophage?
A 31P, 35S
B 31P, 32S
C 31P, 14C
D 31P, 12C

Answer: 31P, 35S
6 Recently, scientists have developed a procedure in which protoplasts of E. coli could be directly infected with the phage DNA. This process is termed as_________
A Transformation
B Transduction
C Transfection
D Mutation

Answer: Transfection
7 According to Mendel’s experiments gene carry genetic information from parents to offspring’s. On which plant did he perform his experiments?
A Oryza sativa
B Pisum sativam
C Allium cepa
D Vitis vinifera

Answer: Pisum sativam
8 Plasmids are ____________
A Double stranded DNA
B Circular double stranded DNA
C Linear double stranded DNA
D Supercoiled circular double stranded DNA

Answer:Circular double stranded DNA
9 What stores the genetic information in DNA?
A Sugar
B Phosphate
C Nitrogenous base
D Polymerase

Answer:Nitrogenous base
10 DNA always carries the genetic information for all organisms.
A True
B False

Answer: False
11 What is the major type of RNA produced in the cell required for translation?
A mRNA
B tRNA
C rRNA
D siRNA

Answer:rRNA
12 Which macromolecule is not abundantly found though being of critical importance for biological mechanisms?
A Proteins
B Lipids
C Nucleic acids
D Polysaccharides

Answer: Lipids
13 Which of the following is wrongly paired?
A Proteins – peptide bond
B Nucleic acid – hydrogen bond
C Polysaccharide – glycosidic bond
D Phospholipids –phosphate linkage

Answer: Nucleic acid – hydrogen bond
14 With respect to nucleosides which of the following is paired correctly?
A Purine – Adenosine, Thymidine
B Purine – Guanosine, Thymidine
C Pyrimidine – Uridine, Cytidine
D Pyrimidine – Uridine, Adenosine

Answer: Pyrimidine – Uridine, Cytidine
15 Which of the following is not a component of the nucleic acid backbone?
A Pentose sugar
B Phosphate group
C Nucleotide
D Phosphodiesterase bond

Answer: Nucleotide
16 According to Chargaff’s rule the two strands of DNA has ___________
A Same molecular weight
B Same amount of A and G
C Different amount of A and G
D Different molecular weight

Answer:Different molecular weight
17 In one strand of a double stranded DNA the rate of occurrence of A is 3 times C in consecutive 10 bases. So how many G will be there in 100 base pairs of a DNA duplex?[Consider G=T in one strand].
A 30
B 20
C 40
D 60

Answer: 40
18 In a diploid organism with 30,000 bases haploid genome contains 23% A residues. What is the number of G residues in the genome of this organism?
A 16000
B 16200
C 16500
D 14200

Answer: 16200
19 Which of the following is not a characteristic of nucleotide bases?
A Planar
B Heterocyclic
C Aliphatic
D Ubiquitous

Answer: Pleiotropism
20 Which of the following factors do not provide to the separation of DNA fragments during electrophoresis?
A Chargaff’s rule
B Matrix density
C Ethidium bromide
D Size

Answer:Ethidium bromide

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