JOIN ADRE 2.0 Telegram Group

Molecular Basis of Inheritance MCQs | Very Short Questions with Answers on Molecular Basis of Inheritance

Questions
1 The process of electrophoresis is the key to sequencing.
A True
B False

Answer:True
2 The dideoxy method is also known as _____________
A Maxem and Gilbert method
B Autosequencing
C Sanger’s enzymatic sequencing
D Pyrosequencing

Answer: Sanger’s enzymatic sequencing
3 Which enzyme is used for the replication in case of Sanger’s method of sequencing?
A Polymerase I
B Smaller subunit polymerase I
C Polymerase III
D Larger subunit polymerase I

Answer: Larger subunit polymerase I
4 With respect to Sanger’s enzymatic method of sequencing pick the odd one out.
A Radioactive dideoxyribonucleotides
B Primers
C Klenow fragment
D Restriction digestion

Answer:Restriction digestion
5 The four reaction mixtures that were prepared, contained ____________
A dCTP, dTTP, dGTP, dATP
B dCTP, ddTTP, dGTP, ddATP
C ddCTP, dTTP, ddGTP, dATP
D dCTP, ddTTP, dGTP, dATP

Answer: dCTP, ddTTP, dGTP, dATP
6 ddNTP acts as the chain radioactive markers.
A True
B False

Answer:False
7 Strand separation for DNA sequencing is done to ____________
A sort the fragments according to their size
B sort the fragments according to their molecular weight
C obtain consecutive sequence as per termination
D obtain specific lanes of sequencing

Answer: obtain consecutive sequence as per termination
8 The position of band during electrophoresis indicates the dNTP used as a chain terminator in that mixture.
A True
B False

Answer:False
9 Automated sequencing is defined as _________
A Chain termination sequencing
B Radio labeled sequencing
C Real time fluorescence sequencing
D Pyrosequencing

Answer:Real time fluorescence sequencing
10 Automated sequencing uses _____________
A Enzymatic process
B Radiolabelling
C Chain termination
D Fluorescent tagging

Answer:Fluorescent tagging
11 No chain termination takes place in automated sequencing.
A True
B False

Answer:False
12 As different fluorescent tags affect the mobility of fragments thus only one type of tag is used.
A True
B False

Answer: False
13 With respect to automated sequencing which of the following is true?
A Detected by radioactive tags
B Multiple plane sequencing
C Horizontal scanning one sequence per lane
D Vertical reading software incorporation

Answer:Horizontal scanning one sequence per lane
14 Which of the following feature is required for the high sensitivity of the tags used for autosequencing?
A Strong absorption at UV spectrum
B Maximum emittion at different wavelengths
C Different mobility shifts
D Induce circularization of DNA fragments

Answer: Maximum emittion at different wavelengths
15 Automated sequencing is a real time one trial method of sequencing and is highly handy.
A True
B False

Answer:False
16 A third generation sequencing can sequence upto ____________nucleotides per day.
A 750000
B 75000
C 570000
D 57000

Answer:750000
17 Semiconservative nature of replication of eukaryotic chromosome was first demonstrated by _______________
A Walter Flemming on root tip cells of Vicia faba
B J. Herbert Taylor, Philip Wood and Walter Hughes on root tip cells of Vicia faba
C Walter Flemming on root tip cells of Phaseolus vulgaris
D J. Herbert Taylor, Philip Wood and Walter Hughes on root tip cells of Phaseolus vulgaris

Answer:J. Herbert Taylor, Philip Wood and Walter Hughes on root tip cells of Vicia faba
18 Pick the correct pair with respect to primers used in DNA replication.
A RNA primer- for prokaryotes only
B DNA primer-for eukaryotes only
C DNA primer- for both prokaryotes and eukaryotes
D RNA primer- for both prokaryotes and eukaryotes

Answer:RNA primer- for both prokaryotes and eukaryotes
19 Which of the following is correctly matched with its subsequent role?
A Topoisomerase II- can remove both positive and negative supercoil in the DNA duplex
B Polymerase I- larger fragment responsible for exonuclease activity
C DnaA protein- responsible for “melting” of the DNA double helix during replication
D DnaB protein- attaches to the newly unwounded single strand of DNA to prevent folding of the strand

Answer: DnaA protein- responsible for “melting” of the DNA double helix during replication
20 Replication fork is the junction between the two ___________
A Unreplicated DNA
B Newly synthesized DNA
C Newly separated DNA strands and newly synthesized DNA strands
D Newly separated DNA strands and the unreplicated DNA

Answer: Newly separated DNA strands and the unreplicated DNA

ADRE 2.0 FULL LENGTH MOCK TEST

Take Mock Tests

Missiles Mock Test Start Test!
SSC MTS Mock Test Start Test
IBPS CLERK MOCK TEST Start Test
SSC MTS 2022 JULY 26 Shift 1 (ENGLISH) Start Test!
SSC GD Previous Year Paper 2021 Nov 17 Shift - I (Hindi) Start Test!
SSC CGL Tier - 1 PYP 2022 April 21 Shift- 1 (ENGLISH) Start Test!
MPSC PAPER I MOCK TEST 1 (ENGLISH) Start Test!
IB Security Assistant Mock test 1 (english) Start Test!
UP POLICE CONSTABLE MOCK TEST 1 Start Test!
DELHI POLICE CONSTABLE MOCK TEST 1 (HINDI) Start Test!
Advertisement
Assam Direct Recruitment Test Series