Questions
1
Amino acids prior to their incorporation into polypeptide must be attached to a special adaptor molecule. Who proved this and when?
Answer:Paul C. Zamecnic and Maholon B. Hoagland in 1957
2
With respect to polymerization of amino acids which of the following statements is wrong?
Answer:The polymerization machinery consists of fifty proteins and two RNA molecules
3
Ribosome begins its translation at the 3’ end of the mRNA in prokaryotes.
Answer:False
4
Check which one of the following mechanisms is wrongly paired with its location of occurrence?
Answer:Post transcriptional mechanism – ER
5
With respect to the subunits of ribosome which of the following is wrongly paired?
Answer: Large subunit = decoding center
7
What is the actual substrate for each round of amino acid addition?
Answer:tRNA
8
The reaction to form a new peptide bond is known as the peptidyl transferase reaction.
Answer:True
9
Where does ribosome gets the energy for the formation of peptide bond?
Answer: Breaking of acyl bond
10
With respect to the mRNA – ribosome complex for translation mechanism which of the following pair is wrong?
Answer:E site – polypeptide exit site
11
Only a single stranded RNA can pass through the ribosome for decoding.
Answer: True
14
With respect to the open reading frame (ORF) which of the following is wrong?
Answer: ‘AUG’ is the only start codon for both prokaryotes and eukaryotes
15
With respect to polycistronic mRNAs which of the following is wrong?
Answer:Found in eukaryotes
17
Which part of the ribosome identifies the Shine – Dalgarno sequence?
Answer:16S rRNA
18
Eukaryotic mRNAs recruit ribosomes using the Shine – Dalgarno sequence.
Answer: False
20
Which one of the following is known as the Kozak sequence?
Answer:5’…..GNNAUGG…..3’
