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Free download in PDF GK Questions and Answers on Molecular Basis of Inheritance for competitive exams. These short objective type questions with answers are very important for Board exams as well as competitive exams like NEET, AIIMS, JIPMER etc. These short solved questions or quizzes are provided by Gkseries./p>
(1)
Binding of polymerase III and helicase ensures helicase efficiency.
(2)
Association of primase with DNA template is brought about by the interaction of primase with _________________
[A]
Dna polymerase III
[B]
Clamp-loader complex
[C]
Helicase and SSB protein
[D]
τ protein
Answer: Helicase and SSB protein
(3)
How is the strength of the interaction between primase and helicase which regulates the length of Okazaki fragments?
[A]
Weak association short fragment
[B]
Strong association short fragment
[C]
Strong association long fragment
[D]
Does not depend on strength of association
Answer: Strong association short fragment
(4)
Which of the following enzyme is not required for the synthesis of lagging strand?
[A]
Primase
[B]
Gyrase
[C]
Helicase
[D]
Exonuclease
(5)
Length of Okazaki fragments in eukaryotes ranges between ____________ nucleotides.
[A]
100 – 400
[B]
400 – 800
[C]
800 – 1200
[D]
1200 – 1600
(6)
Polymerization of dNTP by DNA polymerase is in 3’ → 5’ direction.
(7)
Polymerization of dNTP by DNA polymerase is in 3’ → 5’ direction.
(8)
The origin of replication is rich in __________
[A]
A, T
[B]
G, C
[C]
A, G
[D]
C, T
(9)
How many origin of replication are present in the E. coli genome ___________
[A]
1
[B]
100
[C]
Uncountable
[D]
None
(10)
There are two repeated motifs critical for ori C function. They are ___________
[A]
9 mer and 18 mer
[B]
6 mer and 9 mer
[C]
9 mer and 13 mer
[D]
13 mer and 18 mer
(11)
With respect to the ori C motif choose the correctly paired option.
[A]
9 mer = 9 times
[B]
9 mer = 3 times
[C]
13 mer = 5 times
[D]
13 mer = 3 times
(12)
Which of the following is not paired with its correct function?
[A]
9 mer = binding site for Dna A
[B]
13 mer = binding site for replication initiator protein
[C]
AT rich DNA = unwinding site
[D]
Dna A = replication initiator protein
Answer: 13 mer = binding site for replication initiator protein
(13)
Which of the following is not a function of Dna A?
[A]
DNA binding
[B]
DNA strand separation
[C]
Initiates DNA melting
[D]
Replication protein recruitment
Answer: Initiates DNA melting
(14)
The replication terminus is a segment of a number of ____________ bp.
[A]
350
[B]
350000
[C]
530
[D]
530000
(15)
The replication terminus involves ____________ identical non palindromic termination site.
(16)
The termination sites are one way valves known as non-polar valves.
(17)
The arrest of replication fork motion at Ter sites require the action of ____________ protein.
[A]
Tus
[B]
Ter
[C]
Helicase
[D]
Topoisomerase
(18)
The topological unlinking of DNA in prokaryotes is promoted by ______________
[A]
Helicase
[B]
Topoisomerase
[C]
Tus
[D]
Dna C
(19)
Helicase attaches to the leading strand during replication.
(20)
The primer used for lagging strand synthesis in prokaryotes is an RNA primer.
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