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Free download in PDF Molecular Basis of Inheritance Short Questions and Answers for competitive exams. These short objective type questions with answers are very important for Board exams as well as competitive exams like NEET, AIIMS, JIPMER etc. These short solved questions or quizzes are provided by Gkseries./p>
(1)
How does telomerase activity depend on age?
[A]
Directly
[B]
Inversely
[C]
Remains the same
[D]
Does not occur
(2)
In cancer telomerase activity __________
[A]
Increases
[B]
Decreases
[C]
Remains constant
[D]
Plays no role
(3)
During DNA cloning which of the following is not a crucial requirement?
[A]
DNA inserts
[B]
Vector
[C]
Protein expression
[D]
Molecular cutter
Answer: Protein expression
(4)
Transformation does not involve ____________
[A]
Cutting
[B]
Recombination
[C]
Propagation
[D]
Expression
(5)
Which is the most common organism considered for genetic manipulations?
[A]
E. coli
[B]
Saccharomyces cerevisiae
[C]
Cyanobacteria
[D]
Bacillus Subtilis
(6)
Which of the following is an essential feature for being a perfect vector?
[A]
Origin of replication
[B]
Selectable marker
[C]
Restriction site
[D]
Virulent gene
(7)
DNA ligase can ligate restriction site ends produced by EcoRI to the ends of DNA insert cut by the same enzyme.
(8)
The vector and the DNA insert are cut by different enzymes for convenience.
(9)
What is the major difference between cloning vectors and primary vectors?
[A]
Selectable marker
[B]
DNA inserts
[C]
Presence of promoter
[D]
Presence of two Ori
Answer: Presence of promoter
(10)
Which of the following is the primary use of an expression vector?
[A]
DNA library
[B]
DNA purification
[C]
Protein production
[D]
DNA cloning
Answer: Protein production
(11)
Under the influence of which ion does E. coli takes up plasmid from the environment?
[A]
Nickel
[B]
Copper
[C]
Lead
[D]
None of these
(12)
The process by which every type of transformant can be identified is __________
[A]
Replica plating
[B]
Hybridization
[C]
Blotting
[D]
Insertional inactivation
Answer: Insertional inactivation
(13)
Which of the following does not affect the formation of hybrid DNA?
[A]
Ionic strength
[B]
Pressure
[C]
Temperature
[D]
Homologous DNA
(14)
Which of the following is not termed as hybridization?
[A]
DNA and cDNA
[B]
DNA and mRNA
[C]
DNA from different species
[D]
DNA from male and female of same species
Answer: DNA from male and female of same species
(15)
What is a probe?
[A]
Chemically synthesized DNA
[B]
Purified DNA
[C]
Fragmented DNA duplex
[D]
Either purified or synthesized single stranded DNA
Answer: Either purified or synthesized single stranded DNA
(16)
Why is a probe labeled?
[A]
Improve visibility
[B]
Improve stability
[C]
Improve location identification
[D]
Improve binding capability
Answer: Improve location identification
(17)
In how many ways a DNA can be labeled?
(18)
What is the function of polynucleotide kinase?
[A]
Addition of γ – phosphate at 3’ – OH
[B]
Addition of γ – phosphate at 5’ – OH
[C]
Removal of γ – phosphate at 3’ – OH
[D]
Removal of γ – phosphate at 5’ – OH
Answer: Addition of γ – phosphate at 5’ – OH
(19)
Fluorescent labeling is an important phenomenon in case of hybridization and manipulations in molecular biology.
(20)
Radiolabelling is generally brought about by addition of radioactive phosphorus.
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