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Free download in PDF Short Questions and Answers on Molecular Basis of Inheritance for competitive exams. These short objective type questions with answers are very important for Board exams as well as competitive exams like NEET, AIIMS, JIPMER etc. These short solved questions or quizzes are provided by Gkseries./p>
(1)
With respect to the composition of the ribosome which of the following is correct?
[A]
Ribosome is composed of 60S and 30S subunit
[B]
Eukaryotic ribosome small subunit contains only one 16S rRNA
[C]
60S subunit consists of 5S rRNA and 23S rRNA
[D]
60S and 40S makes up the 80S ribosome
Answer: 60S and 40S makes up the 80S ribosome
(2)
Which element of the ribosome plays a key role in mRNA translation?
[A]
rRNA of the large subunit
[B]
Proteins of the large subunit
[C]
rRNA of the small subunit
[D]
Proteins of the small subunit
Answer: rRNA of the small subunit
(3)
The 3’ end of tRNA is __________
[A]
3’ CCA 5’
[B]
3’ ACC 5’
[C]
3’ CCG 5’
[D]
3’ GCC 5’
(4)
Thymine is present in tRNA.
(5)
With respect to tRNA which of the following is not its characteristic?
[A]
Complimentary region
[B]
Double helix molecule
[C]
Highly conserved pattern of fold
[D]
Variable loop
Answer: Double helix molecule
(6)
How many loops are present in the clover leaf model of tRNA?
(7)
In the beads on a string model, the bead is made up of __________
[A]
6 histone proteins
[B]
8 histone proteins
[C]
6 histone proteins and DNA
[D]
8 histone proteins and DNA
Answer: 8 histone proteins
(8)
The unpacked stretches of DNA are the extra chromosomal load found in the eukaryotic genome.
(9)
How many types of histone molecules are found in nature?
(10)
Nucleosome is made up of __________
[A]
DNA, histone core protein
[B]
DNA, histone core protein, linker H1
[C]
RNA, histone core protein
[D]
RNA, histone core protein, linker H1
Answer: DNA, histone core protein, linker H1
(11)
Histones have a high content of negatively charged amino acids.
(12)
With respect to assembly of every core histone which of the following is wrong?
[A]
A conserved region
[B]
Histone fold domain
[C]
Disc shaped structure
[D]
2 α helices and an unstructured loop
Answer: 2 α helices and an unstructured loop
(13)
Which of the following histone pairs forms tetramers in solution?
[A]
H1, H2A
[B]
H2A, H2B
[C]
H2B, H3
[D]
H3, H4
(14)
With respect to the “tails” of the histone molecules which of the following is not true?
[A]
N – terminal extension
[B]
Lacks defined structure
[C]
Required for the association of nucleosome
[D]
Sites for extensive modifications
Answer: Required for the association of nucleosome
(15)
How many contacts are observed between the DNA and the histone core protein?
[A]
14
[B]
21
[C]
54
[D]
17
(16)
Association of DNA and histone is mediated by _________
[A]
Covalent bonding
[B]
Hydrogen bonding
[C]
Hydrophobic bonding
[D]
Vander Waals interactions
(17)
Histone H1 binds two DNA helices.
(18)
The distinct zig-zag appearance of the chromatin fibre is due to ____________
[A]
Nucleosome
[B]
Histone H1
[C]
Histone core
[D]
Linker DNA
(19)
With respect to Histone H1 DNA packaging which of the following is false?
[A]
H1 induce 10 nm fibre formation
[B]
H1 binding gives nucleosome a defined angle
[C]
H1 stabilizes higher order chromatin structures
[D]
H1 binds to two DNA helices at once
Answer: H1 induce 10 nm fibre formation
(20)
With respect to the solenoid model of nucleosome, which of the following is true?
[A]
Helical model
[B]
8 nucleosomes per turn
[C]
Structure supported by X – ray diffraction
[D]
Helical pitch of approximately 13 nm
Answer: Structure supported by X – ray diffraction
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