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Free download in PDF Molecular Basis of Inheritance Multiple Choice Questions with Answers for competitive exams. These short objective type questions with answers are very important for Board exams as well as competitive exams like NEET, AIIMS, JIPMER etc. These short solved questions or quizzes are provided by Gkseries./p>
(1)
The fluorescent dye such Ethidium is used for visualizing DNA. How do ethidium binds to DNA?
[A]
Stacked between histone molecules
[B]
Binds to the nucleotide base
[C]
Intercalated between the stacked bases
[D]
Binds to the phosphodiester backbone
Answer: Intercalated between the stacked bases
(2)
Pulse field gel electrophoresis separates DNA molecules of size ___________
[A]
10 – 20 bp
[B]
20 – 30 Kb
[C]
30 – 50 Kb
[D]
40 – 50 bp
(3)
Which of the following will migrate faster? The condition is the molecular weight of the following is equal.
[A]
Supercoiled circular DNA
[B]
Nicked circular DNA
[C]
Single stranded DNA
[D]
Double stranded DNA
Answer: Supercoiled circular DNA
(4)
Agarose can be extracted from which of the following?
[A]
Gracilaria esculentus
[B]
Lycazusican esculentum
[C]
Ficum benghalensis
[D]
Agrostis stolonifera
Answer: Gracilaria esculentus
(5)
Electrophoresis cannot be used to separate _______________
[A]
DNA
[B]
RNA
[C]
Amino acid
[D]
Protein
(6)
Which of the following is not a character of polyacrylamide gel?
[A]
Inert
[B]
Ionic strength
[C]
Stable over a wide range of pH
[D]
Separate upto a few 100 bp of DNA
Answer: Separate upto a few 100 bp of DNA
(7)
Pulse field gel electrophoresis was developed by ____________
[A]
Collins and John
[B]
Kary Mullis
[C]
Patrick O’ Farrell
[D]
Schwartz and Cantor
Answer: Schwartz and Cantor
(8)
What is the condition required to observe B form of DNA?
[A]
Low humidity
[B]
High humidity
[C]
Low temperature
[D]
High temperature
(9)
What is the condition required to observe A form of DNA?
[A]
Low humidity
[B]
High humidity
[C]
Low temperature
[D]
High temperature
(10)
How many bases are there in per turn of the B form of DNA?
[A]
8 bp
[B]
9 bp
[C]
10 bp
[D]
11 bp
(11)
Which of the following is not a character of A DNA?
[A]
Short and broad
[B]
Left handed helix
[C]
Narrow minor groove
[D]
Broad and shallow major groove
Answer: Left handed helix
(12)
How many bases are there in per turn of the A form of DNA?
[A]
11 bp
[B]
10 bp
[C]
12 bp
[D]
8 bp
(13)
Which of the following is not a character of B form of DNA?
[A]
Longer and thinner
[B]
Right-handed helix
[C]
Narrow minor groove
[D]
Flat major groove
Answer: Flat major groove
(14)
In a right handed DNA the glycosidic bond is in syn configuration.
(15)
In the Z form of DNA the fundamental repeating unit is __________
[A]
Purine – pyrimidine nucleotide
[B]
Purine – pyrimidine dinucleotide
[C]
Purine – pyrimidine tri-nucleotide
[D]
Purine – pyrimidine tetra-nucleotide
Answer: Purine – pyrimidine tetra-nucleotide
(16)
What is the factor responsible for the left-handed helical conformation in Z form of DNA?
[A]
Syn conformation at pyrimidine
[B]
Anti conformation at pyrimidine
[C]
Syn conformation at purine
[D]
Anti conformation at purine
Answer: Anti conformation at purine
(17)
In higher salt concentration the DNA helix assumes the right-handed conformation.
(18)
The two strands of cccDNA can be easily separated without any breakage of bonds.
(19)
Passing of one strand through the other in order to get separated is known as _______
[A]
Twist
[B]
Linking number
[C]
Writhing number
[D]
Toroid
(20)
Linking number is always a ___________
[A]
Whole number
[B]
Prime number
[C]
Integer
[D]
Even number
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