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Free download in PDF Objective Type Questions and Answers on Molecular Basis of Inheritance for competitive exams. These short objective type questions with answers are very important for Board exams as well as competitive exams like NEET, AIIMS, JIPMER etc. These short solved questions or quizzes are provided by Gkseries./p>
(1)
Which one of the following is not a function of a nucleotide?
[A]
Nucleic acid monomer
[B]
Ribozyme
[C]
Energy carrier molecules
[D]
Receptors
(2)
The first X-ray diffraction patterns of DNA were taken in 1938 by ___________
[A]
William Asbury
[B]
Rosalind Franklin
[C]
Francis H. Crick
[D]
Linus Pauling
(3)
In early 1950s high quality X-ray diffraction photographs of DNA suggesting the DNA being double helix and composed of two nucleotide strands. Who took those photographs?
[A]
Rosalind Franklin
[B]
William Asbury
[C]
Francis H. Crick and James D. Watson
[D]
Rosalind Franklin and Maurice Wilkins
Answer: Rosalind Franklin and Maurice Wilkins
(4)
In 1952, an unambiguous established work in the laboratory of Alexander Todd led to the discovery of _____________
[A]
Chemical nature of DNA
[B]
X-ray diffraction structure of DNA
[C]
3’-5’ phosphodiester linkage regularly links the nucleotides of DNA
[D]
Nucleic acid strands are held together by hydrogen bonds
Answer: 3’-5’ phosphodiester linkage regularly links the nucleotides of DNA
(5)
What should be the complementary strand of 3’….ATGGCTTGA….5’?
[A]
3’….TACCGAACT….5’
[B]
5’….TACCGAACT….3’
[C]
3’….TAGGCAAGT….5’
[D]
5’….TAGGCAAGT….3’
Answer: 5’….TACCGAACT….3’
(6)
The hydrogen bonds formed during A and T bonding occurs between C6NH2 of A and __________
[A]
C4O of T
[B]
PO3–
[C]
C6O of A
[D]
C1O of T
(7)
In a DNA double helix the bases are held together by hydrogen bonds. These hydrogen bonds are _________
[A]
Covalent bonds
[B]
Non-covalent bonds
[C]
Ionic bonds
[D]
Van der Waals forces
Answer: Non-covalent bonds
(8)
It is easy to break the bond between A and T than in between G and C.
(9)
With respect to the importance of hydrogen bonding and DNA double helix stability, which of the following statements is false?
[A]
Favorable tautomeric form of nucleotide bases
[B]
Contributes to the thermodynamic stability
[C]
Decreases the entropy
[D]
Specificity of base pairing
Answer: Decreases the entropy
(10)
In the late 1970s non double helical form of DNA was also suggested but was discarded on the basis of certain factors. Which of the following is not a factor responsible?
[A]
X-ray crystallography
[B]
Nuclein
[C]
Topoisomerase
[D]
Nucleosome core particle
(11)
Levene investigated and found that the nucleic acid is composed of poly-nucleotides and each nucleotide is composed of one base, a sugar molecule and a phosphate. This was performed on the genome of________________
[A]
Bacteria
[B]
Fungi
[C]
WBCs
[D]
Yeast
(12)
Who were the first to suggest that one strand of DNA might act as a template for the synthesis of its complementary strand?
[A]
Meselson and Stahl
[B]
Watson and crick
[C]
Walter Flemming
[D]
Rosalind Franklin and Maurice Wilkins
(13)
Semiconservative nature of replication of eukaryotic chromosome was first demonstrated by _______
[A]
Walter Flemming on root tip cells of Vicia faba
[B]
J. Herbert Taylor, Philip Wood and Walter Hughes on root tip cells of Vicia faba
[C]
Walter Flemming on root tip cells of Phaseolus vulgaris
[D]
J. Herbert Taylor, Philip Wood and Walter Hughes on root tip cells of Phaseolus vulgaris
Answer: J. Herbert Taylor, Philip Wood and Walter Hughes on root tip cells of Vicia faba
(14)
Watson and Crick’s suggestion of the complementary strand synthesis taking one of the parent strand as template was proposed in _________
[A]
1869
[B]
1909
[C]
1953
[D]
1952
(15)
Which of the following statements is true with respect to the DNA double helix?
[A]
Composed of two or more polynucleotide chains
[B]
The base pairs have opposite polarity
[C]
Covalent bond exists in base pairing
[D]
T is transcribed as U
Answer: The base pairs have opposite polarity
(16)
Who, in which year showed firm enzymological proof that DNA alone functions as the template for the synthesis of new DNA strands?
[A]
Watson and Crick in 1953
[B]
Avery, MacCarty and Macleod in 1944
[C]
Meselson and Stahl in 1958
[D]
Hershey and Chase in 1952
Answer: Meselson and Stahl in 1958
(17)
Replication of DNA ends are carried out by polymerase.
(18)
Which of the following regarding the basic mechanism of gene expression is correct?
[A]
DNA ―> tRNA ―> protein
[B]
RNA ―> cDNA ―> mRNA ―> protein
[C]
RNA ―> DNA ―> mRNA ―> protein
[D]
DNA ―> protein
Answer: RNA ―> cDNA ―> mRNA ―> protein
(19)
Which of the following does not take part in gene expression?
[A]
Replication
[B]
Transcription
[C]
RNA processing
[D]
Translation
(20)
Multiple copies of RNA could be formed at the same time.
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