Biopharmaceuticals - Questions and Answers for Competitive Exams | GkSeries

13. The virus used as vector in gene therapy include _______.

• [A] oncoretrovirus
• [B] adenovirus
• [C] herpes virus.
• [D] all the above

Answer: Option [D]

14. Which of the following viral vectors are most often used in clinical gene therapy trials?

• [A] Lentiviral vectors.
• [B] Adenoviral vectors.
• [C] Vaccinia vectors.
• [D] Adeno-associated viral vectors.

Answer: Option [B]

15. Which of the following can carry a large amount foreign DNA with them?

• [A] Retrovirus
• [B] Adenovirus
• [C] Adeno-associated virus.
• [D] Herpes simplex virus.

Answer: Option [B]

16. The anti sense therapy is used to target _______.

• [A] RNA
• [B] carbohydrate
• [C] protein
• [D] lipids

Answer: Option [C]

17. The anti sense oligonucleotide is used in the treatment of _______.

• [A] typhoid
• [B] malaria
• [C] tuberculosis
• [D] cancer

Answer: Option [D]

18. How many phases of clinical trials exist to approve a drug?

• [A] 1
• [B] 2
• [C] 4
• [D] 3

Answer: Option [C]

19. The anti cancer agent include _______.

• [A] taxol
• [B] docetaxel
• [C] camptothecin
• [D] all the above.

Answer: Option [D]

20. The snake venom provide rich source of active molecule that address the _______.

• [A] ion channel.
• [B] receptor with high affinity
• [C] selectivity.
• [D] all the above.

Answer: Option [D]

21. If an agonist can produce maximal effects and has high efficacy its called

• [A] Partial agonist
• [B] Antagonist
• [C] Agonist-antagonist
• [D] Full agonist

Answer: Option [D]

22. The commonly used assay system include _______.

• [A] C.elegans.
• [B] mouse
• [C] D.melangaster.
• [D] all the above.

Answer: Option [D]

23. The key ingredients in the docking include _______.

• [A] representation of the system.
• [B] conformational space search.
• [C] ranking of potential solution.
• [D] all the above.

Answer: Option [D]

24. The protein molecular modeling by computers is used to study _______.

• [A] homology
• [B] threading
• [C] ab initio prediction
• [D] all the above.

Answer: Option [D]