Biopharmaceuticals - Questions and Answers for Competitive Exams | GkSeries

37. Which of the following strategies cannot be used for targeting tumor cells?

• [A] Cocktails of different MAb attached to the toxin
• [B] create by-stander effect
• [C] Injection of free MAb prior to injection of the immunoconjugate
• [D] Use of specific antibodi

Answer: Option [D]

38. The process in which the synthesis of more complex molecule than a lead derivative is called _______

• [A] transjoining
• [B] metabolic addition.
• [C] conjunction
• [D] lead conjugation.

Answer: Option [C]

39. _______ is the mixture of aminopyrine and barbital.

• [A] Sideromone
• [B] Veramon
• [C] Salicylic acid.
• [D] Methenamine mandelate.

Answer: Option [B]

40. The functional assay of high throughput screening measure the _______ of a compound in modifying the actual function of a target protein.

• [A] activity
• [B] binding
• [C] interaction
• [D] affinity

Answer: Option [A]

41. The microtiter plates used in HTS contains _______.

• [A] benzene
• [B] piperidine
• [C] DMSO
• [D] pyridine

Answer: Option [C]

42. The essential tools in pharmacokinetics is _______.

• [A] bioavailability
• [B] solubility
• [C] permeability
• [D] all the above.

Answer: Option [D]

43. The low permeability and high solubility corresponds to _______.

• [A] Class I.
• [B] Class II.
• [C] Class III.
• [D] Class IV.

Answer: Option [C]

44. The strong inter molecular interaction results in the _______.

• [A] good aqueous solubility.
• [B] very good aqueous solubility.
• [C] poor aqueous solubility.
• [D] intermediate aqueous solubility.

Answer: Option [C]

45. Cetyl pyridinium bromide(CPB) acts as _______.

• [A] tumoricidal agent.
• [B] insecticidal agent.
• [C] germicidal agent.
• [D] herbicidal agent.

Answer: Option [C]

46. The alkaloid that do not contain nitrogen atom include _______.

• [A] carotene
• [B] piperine
• [C] adrenaline
• [D] solamine

Answer: Option [C]

47. Carotenoids are usually made of _______.

• [A] benzene rings.
• [B] amino benzene.
• [C] phenolic compounds.
• [D] isoprene units.

Answer: Option [D]

48. Which of the following is not a reporter gene

• [A] kinase
• [B] luciferase
• [C] GFP
• [D] RFP

Answer: Option [A]