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Free download in PDF Molecular Basis of Inheritance Objective Type Questions with Answers for competitive exams. These short objective type questions with answers are very important for Board exams as well as competitive exams like NEET, AIIMS, JIPMER etc. These short solved questions or quizzes are provided by Gkseries./p>
(1)
Type I topoisomerase can never decatenate catenated circular DNA?
(2)
The promotion of DNA breaking and rejoining by topoisomerase requires______________
[A]
High – energy cofactor
[B]
Ligase
[C]
DNase I
[D]
No external enzyme required
Answer: No external enzyme required
(3)
Attack of the topoisomerase gives rise to ____________
[A]
Hydroxy – valine linkage
[B]
Phospho – tyrosine linkage
[C]
Hydroxy – cystine linkage
[D]
Phospho – proline linkage
Answer: Phospho – tyrosine linkage
(4)
To reseal the DNA backbone where does topoisomerase gets the energy from?
[A]
ATP hydrolysis
[B]
High energy cofactor
[C]
Phosphodiester cleavage
[D]
Phosphotyrosine cleavage
Answer: Phosphodiester cleavage
(5)
Which of the following does not occur during cell division in prokaryotes?
[A]
Multiple decatenations
[B]
DNA cleavage
[C]
DNA rejoining
[D]
Strand passage
Answer: Multiple decatenations
(6)
The active site of the topoisomerase contains a tyrosine residue.
(7)
Nucleosome was first described in 1974 by ___________
[A]
William Asbury
[B]
Rosalind Franklin
[C]
Roger Kornberg
[D]
John Crick
(8)
The extent of chromosome coiling in non – dividing cells is _________
[A]
Supercoiled
[B]
Euchromatin
[C]
Condensed
[D]
Heterochromatin
(9)
The whole length of DNA is transcriptionally active.
(10)
Why are chromosomes condensed?
[A]
To facilitate accommodation
[B]
Always condensed
[C]
To facilitate cell division
[D]
To facilitate distribution in daughter cells
Answer: To facilitate distribution in daughter cells
(11)
At which phase do transcription ceases?
[A]
Interphase
[B]
Prophase
[C]
S phase
[D]
G phase
(12)
The part that plays a critical role in even distribution of parental DNA during division is ___________
[A]
Telomere
[B]
Centromere
[C]
Spindle fibre
[D]
Centrioles
(13)
With respect to centromere which of the following is wrong?
[A]
Constricted chromosomal region
[B]
Holds the sister chromatids together
[C]
Attaches to spindle fibres
[D]
Facilitates even distribution
Answer: Facilitates even distribution
(14)
The protein that binds to the spindle fibres are known as centromeric proteins.
(15)
Centromeric DNA was initially defined in ___________
[A]
Bacteria
[B]
Fungi
[C]
Yeast
[D]
Human
(16)
How many satellite sequence elements are present in yeast centromere?
(17)
The centromere is A/T rich region.
(18)
Which alternate form of histone is seen in centromeric histones of humans?
[A]
H2A.z
[B]
SMC protein
[C]
H1
[D]
CENP-A
(19)
Telomere is not related to __________
[A]
Maintenance
[B]
Chromosome degradation
[C]
Division
[D]
Replication
(20)
Which of the following nucleotides is rich I telomere of an organism?
[A]
A, T
[B]
T, G
[C]
G, C
[D]
C, A
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