NCERT - Molecular Basis of Inheritance Questions and Answers of Class 12 Biology | GkSeries

106 The RNA polymerase holoenzyme transcribes:
[1] the promoter, structural gene and the terminator region
[2] the promoter, and the
[3] the structural gene and the terminator regions
[4] the structural gene only.
Answer: the structural gene and the terminator regions
107 To initiate translation, the mRNA first binds to:
[1] The smaller ribosomal sub-unit
[2] The larger ribosomal sub-unit
[3] The whole ribosome
[4] No such specificity exists.
Answer: The smaller ribosomal sub-unit

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108 Repressor proteins are coded for by ______ genes.
[1] Structural
[2] Operator
[3] Promoter
[4] Regulator
Answer: Regulator
109 The organelles in the cell where protein synthesis occurs are ______.
[1] Endoplasmic reticulum
[2] lNuceus
[3] Ribosomes
[4] mRNA
Answer: Ribosomes
110 PCR and Restriction Fragment Length Polymorphism are the methods fo
[1] DNA sequencing
[2] Genetic fingerprinting
[3] Study of enzymes
[4] Genetic transformation
Answer: Genetic fingerprinting
111 What is antisense technology?
[1] RNA polymerase producing DNA
[2] A cell displaying a foreign antigen used for synthesis of antigens
[3] Production of somaclonal variants in tissue cultures
[4] When a piece of RNA that is complementary in sequence is used to stop expression of a specific gene
Answer: When a piece of RNA that is complementary in sequence is used to stop expression of a specific gene
112 A DNA segment which serves as a kind of “on-off switch” for transcription is a/an ______.
[1] Regulator gene
[2] Structural gene
[3] Promoter
[4] Operator
Answer: Operator
113 Which one of the following does not follow the central dogma of molecular biology?
[1] Pea
[2] Mucor
[3] HIV
[4] Chlamydomonas
Answer: HIV
114 In some viruses, DNA is synthesised by using RNA as template. Such a DNA is called
[1] A-DNA
[2] B-DNA
[3] c DNA
[4] r DNA
Answer: c DNA
115 Discontinuous synthesis of DNA occurs in one strand, because:
[1] DNA molecule being synthesised is very long
[2] DNA dependent DNA polymearse catalyses polymerisation only in one direction (5’ → 3’)
[3] it is a more efficient process
[4] DNA ligase has to have a role
Answer: DNA dependent DNA polymearse catalyses polymerisation only in one direction (5’ → 3’)
116 Both deoxyribose and ribose belong to a class of sugars called:
[1] trioses
[2] hexoses
[3] pentoses
[4] polysaccharides
Answer: pentoses
117 Which of the following statements is the most appropriate for sickle cell anaemia?
[1] It cannot be treated with iron supplements
[2] It is a molecular disease
[3] It confers resistance to acquiring malaria
[4] All of the above
Answer: All of the above
118 Who amongst the following scientists had no contribution in the development of the double helix model for the structure of DNA?
[1] Rosalind Franklin
[2] Maurice Wilkins
[3] Erwin Chargaff
[4] Meselson and Stahl
Answer: Meselson and Stahl
119 Which of the following steps in transcription is catalysed by RNA polymerse?
[1] Initiation
[2] Elongation
[3] Termination
[4] All of the above
Answer: Elongation
120 While analysing the DNA of an organism a total number of 5386 nucleotides were found out of which the proportion of different bases were: Adenine = 29%, Guanine= 17%, Cytosine = 32%, Thymine = 17%. Considering the Chargaff’s rule it can be concluded that:
[1] it is a double stranded circular DNA
[2] It is single stranded DNA
[3] It is a double stranded linear DNA
[4] No conclusion can be drawn
Answer: No conclusion can be drawn

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